The fact that various immune cells including macrophages can be found in tumor tissues has long been known with the introduction of concept that macrophages differentiate into a classically or alternatively activated phenotype the role of tumor associated macrophages tams is now beginning to be elucidated tams act as protumoral macrophages contributing to disease progression . The application of this technology to several aspects of cancer biology ranging from basic research to clinical and translational applications offers numerous exciting opportunities for better understanding and potentially treating this devastating disease use of gene targeting technology in the mouse to study cancer associated genes and . Malignant melanoma is the focus of investigations which range from basic re search to clinical trials with conventional therapy and with biological response modifiers the involvement of investigators with different backgrounds in combi nation with recent progress in biotechnology has facilitated. The ultimate goal of cancer researchers is to translate scientific findings into practical clinical applications experimental discoveries are thought to begin at the bench with basic research progress through pre clinical animal studies then show therapeutic efficacy in human clinical trials. Human melanoma from basic research to clinical application soldano ferrone add tags for human melanoma from basic research to clinical application be the first similar items related subjects 3 melanoma melanome melanom confirm this request you may have already requested this item please select ok if you would like to
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